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Showing 1 to 12 of 201 entries
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Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma.

Oncogenesis

Chauhan R, Churchill ND, Mulrooney-Cousins PM, Michalak TI.
PMID: 28414318
Oncogenesis. 2017 Apr 17;6(4):e317. doi: 10.1038/oncsis.2017.22.

Hepatitis B virus (HBV) and the closely related woodchuck hepatitis virus (WHV) are potent carcinogens that trigger development of primary hepatocellular carcinoma (HCC). The initial sites of hepadnavirus-host genome integration, their diversity and kinetics of formation can be central...

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Chauhan R, Churchill ND, Mulrooney-Cousins PM, et al. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis. 2017;6(4):e317doi: 10.1038/oncsis.2017.22.
Chauhan, R., Churchill, N. D., Mulrooney-Cousins, P. M., & Michalak, T. I. (2017). Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis, 6(4), e317. https://doi.org/10.1038/oncsis.2017.22
Chauhan, R, et al. "Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma." Oncogenesis vol. 6,4 (2017): e317. doi: https://doi.org/10.1038/oncsis.2017.22
Chauhan R, Churchill ND, Mulrooney-Cousins PM, Michalak TI. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis. 2017 Apr 17;6(4):e317. doi: 10.1038/oncsis.2017.22. PMID: 28414318; PMCID: PMC5520499.
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Integrative modules for efficient genome engineering in yeast.

Microbial cell (Graz, Austria)

Amen T, Kaganovich D.
PMID: 28660202
Microb Cell. 2017 Jun 05;4(6):182-190. doi: 10.15698/mic2017.06.576.

We present a set of vectors containing integrative modules for efficient genome integration into the commonly used selection marker loci of the yeast

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Amen T, Kaganovich D. Integrative modules for efficient genome engineering in yeast. Microb Cell. 2017;4(6):182-190doi: 10.15698/mic2017.06.576.
Amen, T., & Kaganovich, D. (2017). Integrative modules for efficient genome engineering in yeast. Microbial cell (Graz, Austria), 4(6), 182-190. https://doi.org/10.15698/mic2017.06.576
Amen, Triana, and Kaganovich, Daniel. "Integrative modules for efficient genome engineering in yeast." Microbial cell (Graz, Austria) vol. 4,6 (2017): 182-190. doi: https://doi.org/10.15698/mic2017.06.576
Amen T, Kaganovich D. Integrative modules for efficient genome engineering in yeast. Microb Cell. 2017 Jun 05;4(6):182-190. doi: 10.15698/mic2017.06.576. PMID: 28660202; PMCID: PMC5473690.
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Investigation of DNA integration into reproductive organs following intramuscular injection of DNA in mice.

Reports of biochemistry & molecular biology

Vahedi F, Nazari N, Arbabi S, Peymanfar Y.
PMID: 26989704
Rep Biochem Mol Biol. 2012 Oct;1(1):21-4.

BACKGROUND: DNA immunization with plasmid DNA encoding bacterial, viral, parasitic, and tumor antigens has been reported to trigger protective immunity. The use of plasmid DNA vaccinations against many diseases has produced promising results in animal and human clinical trials;...

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Vahedi F, Nazari N, Arbabi S, et al. Investigation of DNA integration into reproductive organs following intramuscular injection of DNA in mice. Rep Biochem Mol Biol. 2012;1(1):21-4
Vahedi, F., Nazari, N., Arbabi, S., & Peymanfar, Y. (2012). Investigation of DNA integration into reproductive organs following intramuscular injection of DNA in mice. Reports of biochemistry & molecular biology, 1(1), 21-4.
Vahedi, Fatemeh, et al. "Investigation of DNA integration into reproductive organs following intramuscular injection of DNA in mice." Reports of biochemistry & molecular biology vol. 1,1 (2012): 21-4.
Vahedi F, Nazari N, Arbabi S, Peymanfar Y. Investigation of DNA integration into reproductive organs following intramuscular injection of DNA in mice. Rep Biochem Mol Biol. 2012 Oct;1(1):21-4. PMID: 26989704; PMCID: PMC4757076.
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Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes.

Annual review of virology

Osterrieder N, Wallaschek N, Kaufer BB.
PMID: 26958721
Annu Rev Virol. 2014 Nov;1(1):215-35. doi: 10.1146/annurev-virology-031413-085422. Epub 2014 Jun 27.

It is well known that numerous viruses integrate their genetic material into host cell chromosomes. Human herpesvirus 6 (HHV-6) and oncogenic Marek's disease virus (MDV) have been shown to integrate their genomes into host telomeres of latently infected cells....

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Osterrieder N, Wallaschek N, Kaufer BB. Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes. Annu Rev Virol. 2014;1(1):215-35doi: 10.1146/annurev-virology-031413-085422.
Osterrieder, N., Wallaschek, N., & Kaufer, B. B. (2014). Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes. Annual review of virology, 1(1), 215-35. https://doi.org/10.1146/annurev-virology-031413-085422
Osterrieder, Nikolaus, et al. "Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes." Annual review of virology vol. 1,1 (2014): 215-35. doi: https://doi.org/10.1146/annurev-virology-031413-085422
Osterrieder N, Wallaschek N, Kaufer BB. Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes. Annu Rev Virol. 2014 Nov;1(1):215-35. doi: 10.1146/annurev-virology-031413-085422. Epub 2014 Jun 27. PMID: 26958721.
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Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders.

Genome integrity

Roy S, Chakraborty A, Ghosh C, Banerjee B.
PMID: 27330735
Genome Integr. 2015 Apr 28;6:1. doi: 10.4103/2041-9414.155952. eCollection 2015.

BACKGROUND: Stress is a term used to define factors involved in changes in the physiological balances resulting in disease conditions. Chronic exposure to stress conditions in modern lifestyles has resulted in a group of disorders called lifestyle disorders. Genetic...

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Roy S, Chakraborty A, Ghosh C, et al. Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders. Genome Integr. 2015;6:1doi: 10.4103/2041-9414.155952.
Roy, S., Chakraborty, A., Ghosh, C., & Banerjee, B. (2015). Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders. Genome integrity, 61. https://doi.org/10.4103/2041-9414.155952
Roy, Souvick, et al. "Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders." Genome integrity vol. 6 (2015): 1. doi: https://doi.org/10.4103/2041-9414.155952
Roy S, Chakraborty A, Ghosh C, Banerjee B. Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders. Genome Integr. 2015 Apr 28;6:1. doi: 10.4103/2041-9414.155952. eCollection 2015. PMID: 27330735; PMCID: PMC4911901.
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Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency.

Genome integrity

Doubi S, Amrani Z, Ouahabi HE, Boujraf S, Ajdi F.
PMID: 27330737
Genome Integr. 2015 Sep 16;6:3. doi: 10.4103/2041-9414.165531. eCollection 2015.

Klinefelter syndrome (KS) is characterized in adults by the combination of a tall stature, small testes, gynecomastia, and azoospermia. This case is described in a North African population of the Mediterranean region of North Africa. We report the case...

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Doubi S, Amrani Z, Ouahabi HE, et al. Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency. Genome Integr. 2015;6:3doi: 10.4103/2041-9414.165531.
Doubi, S., Amrani, Z., Ouahabi, H. E., Boujraf, S., & Ajdi, F. (2015). Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency. Genome integrity, 63. https://doi.org/10.4103/2041-9414.165531
Doubi, Sana, et al. "Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency." Genome integrity vol. 6 (2015): 3. doi: https://doi.org/10.4103/2041-9414.165531
Doubi S, Amrani Z, Ouahabi HE, Boujraf S, Ajdi F. Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency. Genome Integr. 2015 Sep 16;6:3. doi: 10.4103/2041-9414.165531. eCollection 2015. PMID: 27330737; PMCID: PMC4911902.
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Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma.

Genomics data

Dong H, Qian Z, Zhang L, Chen Y, Ren Z, Ji Q.
PMID: 26697315
Genom Data. 2015 Jul 22;6:1-3. doi: 10.1016/j.gdata.2015.07.018. eCollection 2015 Dec.

Interaction between HBV and host genome integrations in hepatocellular carcinoma (HCC) development is a complex process and the mechanism is still unclear. Here we described in details the quality controls and data mining of aCGH and transcriptome sequencing data...

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Dong H, Qian Z, Zhang L, et al. Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma. Genom Data. 2015;6:1-3doi: 10.1016/j.gdata.2015.07.018.
Dong, H., Qian, Z., Zhang, L., Chen, Y., Ren, Z., & Ji, Q. (2015). Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma. Genomics data, 61-3. https://doi.org/10.1016/j.gdata.2015.07.018
Dong, Hua, et al. "Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma." Genomics data vol. 6 (2015): 1-3. doi: https://doi.org/10.1016/j.gdata.2015.07.018
Dong H, Qian Z, Zhang L, Chen Y, Ren Z, Ji Q. Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma. Genom Data. 2015 Jul 22;6:1-3. doi: 10.1016/j.gdata.2015.07.018. eCollection 2015 Dec. PMID: 26697315; PMCID: PMC4664659.
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Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery.

Genetic vaccines and therapy

Coelho-Castelo AA, Trombone AP, Rosada RS, Santos RR, Bonato VL, Sartori A, Silva CL.
PMID: 16445866
Genet Vaccines Ther. 2006 Jan 30;4:1. doi: 10.1186/1479-0556-4-1.

In order to assess a new strategy of DNA vaccine for a more complete understanding of its action in immune response, it is important to determine the in vivo biodistribution fate and antigen expression. In previous studies, our group...

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Coelho-Castelo AA, Trombone AP, Rosada RS, et al. Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery. Genet Vaccines Ther. 2006;4:1doi: 10.1186/1479-0556-4-1.
Coelho-Castelo, A. A., Trombone, A. P., Rosada, R. S., Santos, R. R., Bonato, V. L., Sartori, A., & Silva, C. L. (2006). Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery. Genetic vaccines and therapy, 41. https://doi.org/10.1186/1479-0556-4-1
Coelho-Castelo, A A M, et al. "Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery." Genetic vaccines and therapy vol. 4 (2006): 1. doi: https://doi.org/10.1186/1479-0556-4-1
Coelho-Castelo AA, Trombone AP, Rosada RS, Santos RR, Bonato VL, Sartori A, Silva CL. Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery. Genet Vaccines Ther. 2006 Jan 30;4:1. doi: 10.1186/1479-0556-4-1. PMID: 16445866; PMCID: PMC1403771.
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Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning.

Genome integrity

Liu GE, Hou Y, Robl JM, Kuroiwa Y, Wang Z.
PMID: 21605421
Genome Integr. 2011 May 23;2(1):6. doi: 10.1186/2041-9414-2-6.

BACKGROUND: Transgenic cattle carrying multiple genomic modifications have been produced by serial rounds of somatic cell chromatin transfer (cloning) of sequentially genetically targeted somatic cells. However, cloning efficiency tends to decline with the increase of rounds of cloning. It...

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Liu GE, Hou Y, Robl JM, et al. Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning. Genome Integr. 2011;2(1):6doi: 10.1186/2041-9414-2-6.
Liu, G. E., Hou, Y., Robl, J. M., Kuroiwa, Y., & Wang, Z. (2011). Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning. Genome integrity, 2(1), 6. https://doi.org/10.1186/2041-9414-2-6
Liu, George E, et al. "Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning." Genome integrity vol. 2,1 (2011): 6. doi: https://doi.org/10.1186/2041-9414-2-6
Liu GE, Hou Y, Robl JM, Kuroiwa Y, Wang Z. Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning. Genome Integr. 2011 May 23;2(1):6. doi: 10.1186/2041-9414-2-6. PMID: 21605421; PMCID: PMC3123262.
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Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner.

Genome integrity

Lyakhovich A, Ramirez MJ, Castellanos A, Castella M, Simons AM, Parvin JD, Surralles J.
PMID: 21314979
Genome Integr. 2011 Feb 12;2(1):4. doi: 10.1186/2041-9414-2-4.

BACKGROUND: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play...

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Lyakhovich A, Ramirez MJ, Castellanos A, et al. Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner. Genome Integr. 2011;2(1):4doi: 10.1186/2041-9414-2-4.
Lyakhovich, A., Ramirez, M. J., Castellanos, A., Castella, M., Simons, A. M., Parvin, J. D., & Surralles, J. (2011). Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner. Genome integrity, 2(1), 4. https://doi.org/10.1186/2041-9414-2-4
Lyakhovich, Alex, et al. "Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner." Genome integrity vol. 2,1 (2011): 4. doi: https://doi.org/10.1186/2041-9414-2-4
Lyakhovich A, Ramirez MJ, Castellanos A, Castella M, Simons AM, Parvin JD, Surralles J. Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner. Genome Integr. 2011 Feb 12;2(1):4. doi: 10.1186/2041-9414-2-4. PMID: 21314979; PMCID: PMC3048478.
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Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells.

Genome integrity

Asharani P, Sethu S, Lim HK, Balaji G, Valiyaveettil S, Hande MP.
PMID: 22321936
Genome Integr. 2012 Feb 10;3(1):2. doi: 10.1186/2041-9414-3-2.

BACKGROUND: Investigating the cellular and molecular signatures in eukaryotic cells following exposure to nanoparticles will further our understanding on the mechanisms mediating nanoparticle induced effects. This study illustrates the molecular effects of silver nanoparticles (Ag-np) in normal human lung...

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Asharani P, Sethu S, Lim HK, et al. Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr. 2012;3(1):2doi: 10.1186/2041-9414-3-2.
Asharani, P., Sethu, S., Lim, H. K., Balaji, G., Valiyaveettil, S., & Hande, M. P. (2012). Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome integrity, 3(1), 2. https://doi.org/10.1186/2041-9414-3-2
Asharani, Pv, et al. "Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells." Genome integrity vol. 3,1 (2012): 2. doi: https://doi.org/10.1186/2041-9414-3-2
Asharani P, Sethu S, Lim HK, Balaji G, Valiyaveettil S, Hande MP. Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr. 2012 Feb 10;3(1):2. doi: 10.1186/2041-9414-3-2. PMID: 22321936; PMCID: PMC3305596.
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Evolutionary loss of 8-oxo-G repair components among eukaryotes.

Genome integrity

Jansson K, Blomberg A, Sunnerhagen P, Alm Rosenblad M.
PMID: 20809962
Genome Integr. 2010 Sep 01;1(1):12. doi: 10.1186/2041-9414-1-12.

BACKGROUND: We have examined the phylogenetic pattern among eukaryotes of homologues of the E. coli 7,8-dihydro-8-oxoguanine (8-oxo-G) repair enzymes MutY, MutM, and MutT.RESULTS: These DNA repair enzymes are present in all large phylogenetic groups, with MutM homologues being the...

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Jansson K, Blomberg A, Sunnerhagen P, et al. Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome Integr. 2010;1(1):12doi: 10.1186/2041-9414-1-12.
Jansson, K., Blomberg, A., Sunnerhagen, P., & Alm Rosenblad, M. (2010). Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome integrity, 1(1), 12. https://doi.org/10.1186/2041-9414-1-12
Jansson, Kristina, et al. "Evolutionary loss of 8-oxo-G repair components among eukaryotes." Genome integrity vol. 1,1 (2010): 12. doi: https://doi.org/10.1186/2041-9414-1-12
Jansson K, Blomberg A, Sunnerhagen P, Alm Rosenblad M. Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome Integr. 2010 Sep 01;1(1):12. doi: 10.1186/2041-9414-1-12. PMID: 20809962; PMCID: PMC2941479.
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Showing 1 to 12 of 201 entries